MHC, Class I anticorps (CF®740)
Aperçu rapide pour MHC, Class I anticorps (CF®740) (ABIN7657101)
Antigène
Voir toutes MHC, Class I AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- MHC I(246-B8.E7), CF740 conjugate
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Attributs du produit
- Reacts with a monomorphic determinant of human major histocompatibility (MHC) class I antigens (HLA-A, B and C). Human MHC class I antigens are expressed constitutively on all nucleated cells lymphocytes such as lymphocytes, thymocytes, granulocytes, and bone marrow cells and are absent on erythrocytes. MHC class I antigens play a role in class I MHC-associated antigen presentation, inhibition of NK cell cytotoxicity, tumor surveillance, and tissue allotransplantation.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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Immunogène
- Human peripheral blood leukocytes
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Isotype
- IgG2a, kappa
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Indications d'application
- Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Immunofluorescence: 0.5-1 μg/mL. Flow Cytometry 0.5-1 μg/million cells/0.1 mL. Optimal dilution for a specific application should be determined by user
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Commentaires
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Positive Control: THP-1 and Jurkat cells. Tonsil or lymph node.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.1 mg/mL
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Buffer
- PBS, 0.1 % rBSA, 0.05 % azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Protect from light
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Stock
- 4 °C
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Stockage commentaire
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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Date de péremption
- 24 months
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- MHC, Class I
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Autre désignation
- MHC-I
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Sujet
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Synonyms: HLA-A, HLA-B, HLA-C, HLA class 1A, HLA class 1B, HLA class 1C, Major histocompatibility complex, class I, A B C, MHC class I HLA-A, MHC class I HLA-B, MHC class I HLA-C, MHC HLA-ABC
Gene Symbol: HLA-A
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Poids moléculaire
- ~41 kDa
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ID gène
- 3105
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UniProt
- P01889, P30443, P30499
Antigène
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