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MHC, Class I anticorps (CF®740)

Cet anticorps anti-MHC, Class I est un anticorps Souris Monoclonal détectant MHC, Class I dans IF. Adapté pour Souris, Humain et Non-Human Primate.
N° du produit ABIN7657101

Aperçu rapide pour MHC, Class I anticorps (CF®740) (ABIN7657101)

Antigène

Voir toutes MHC, Class I Anticorps
MHC, Class I

Reactivité

  • 71
  • 56
  • 13
  • 9
  • 7
  • 6
  • 5
  • 5
  • 5
  • 5
  • 4
  • 1
Souris, Humain, Non-Human Primate

Hôte

  • 75
  • 47
  • 7
  • 1
Souris

Clonalité

  • 91
  • 36
  • 3
Monoclonal

Conjugué

  • 37
  • 15
  • 13
  • 10
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp MHC, Class I est conjugé à/à la CF®740

Application

  • 87
  • 54
  • 33
  • 25
  • 21
  • 14
  • 14
  • 13
  • 13
  • 11
  • 7
  • 5
  • 5
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
Immunofluorescence (IF)

Clone

246-B8-E7
  • Fonction

    MHC I(246-B8.E7), CF740 conjugate

    Attributs du produit

    Reacts with a monomorphic determinant of human major histocompatibility (MHC) class I antigens (HLA-A, B and C). Human MHC class I antigens are expressed constitutively on all nucleated cells lymphocytes such as lymphocytes, thymocytes, granulocytes, and bone marrow cells and are absent on erythrocytes. MHC class I antigens play a role in class I MHC-associated antigen presentation, inhibition of NK cell cytotoxicity, tumor surveillance, and tissue allotransplantation.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    Immunogène

    Human peripheral blood leukocytes

    Isotype

    IgG2a, kappa
  • Indications d'application

    Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Immunofluorescence: 0.5-1 μg/mL. Flow Cytometry 0.5-1 μg/million cells/0.1 mL. Optimal dilution for a specific application should be determined by user

    Commentaires

    Positive Control: THP-1 and Jurkat cells. Tonsil or lymph node.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.1 mg/mL

    Buffer

    PBS, 0.1 % rBSA, 0.05 % azide

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Protect from light

    Stock

    4 °C

    Stockage commentaire

    Stable at room temperature or 37°C for 7 days.

    Protect from light

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    Date de péremption

    24 months
  • Antigène

    MHC, Class I

    Autre désignation

    MHC-I

    Sujet

    Synonyms: HLA-A, HLA-B, HLA-C, HLA class 1A, HLA class 1B, HLA class 1C, Major histocompatibility complex, class I, A B C, MHC class I HLA-A, MHC class I HLA-B, MHC class I HLA-C, MHC HLA-ABC

    Gene Symbol: HLA-A

    Poids moléculaire

    ~41 kDa

    ID gène

    3105

    UniProt

    P01889, P30443, P30499
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